Wren Building at the West End of Duke of Gloucester Street on the campus of the College of William and Mary in Williamsburg, Virginia on July 25, 2019. With a construction history dating to 1695, it is the oldest academic building in continuous use in the United States. The Blue Room served as the administrative seat of the College throughout the colonial period. Today, the room is used by students defending their doctoral dissertations and honors theses. The portrait is of Margaret, the Lady Thatcher, the first female chancellor of the College since the Revolutionary War.